Stef, the best thing to do is to talk with the Printer person who will be outputing your artwork. As Grim mentioned, you may be able to get by with a lower resolution if the actual printer handles it well enough.

Do you have someone in mind or a type of print output?

Some print shops are able to go to press right from digital so that may be something to look into...

let us know how this progresses, or if you have more questions...

even though i don't think i've helped any ;)

:)
retrocity