In my estimation they are 100% USELESS in Poser and Bryce... marginal in Amorphium and INDESPENSIBLE for post production in Photo Shop (or other drawing application) I have a 4X5 Intous and the Wacom 4D mouse which may be personalized for PhotoShop. The 4X5 is to small for the mouse. I will probably buy a 6X8 in the next few months. Please be aware that a mouse and tablet complement each other. I use my mouse as much as I do the tablet. Christine