BINGO! NVIDIA drivers can do evil things, and each one has its own particular brand of bad juju. I had the same trouble =after= I upgraded the drivers on my GF4-TI4400. Disable the OpenGL and see if that fixes it. If so, you might have to choose between newer 4 in 1's or using GL with Vue. All of the newer drivers are mainly game related improvements, and those tend to not get along with graphics programs.