OK, before I say anything, I am a solid bryce user (have played with the vue demo, but stayed with bryce). I have made some "big, really big" scenes in bryce (check gallery if you want). I imagine you could do the same sort of "big" things in Vue. To my mind, bryce is a bit more versatile than Vue, but if you're looking at using poser stuff heavily, then I'd definitely consider going with Vue mainly for that fairly good Poser/Vue compatibility.

Dreams are just nightmares on prozac...
Digital WasteLanD