Ah, the secret is housekeeping. Start tidying up all those bloated folders, tweak a few textures you've downloaded and never used. Promise yourself to delete or put in storeage at least 10 characters or props you've never touched. Merge a few of the smaller pose folders. In no time at all you'll either have more efficient files for the next time the Muse nips at your ankles or, more probably, you'll have discovered something you'd forgotten you had and suddenly it's 3am.