I've seen this brought up a few times when we've talked about color or brightness shifts when dealing with different colorspaces/programs. While calibration is a very important step in color management, I don't think it applies in this situation. In monitor calibration, you are trying to standardize your brightness and color neutrality so that if you opened the same image on two different monitors (or output it to a printing device) the images would look the same. If there's a calibration problem, opening the same image on different monitors yields a shift in brightness and/or color. With gamut problems, opening the same image on the same monitor with different gamuts gives you a brightness and/or color shift. Now I could imagine a case where it could effect it. But you'd have to have a somewhat large miscalibration where one of the three color gammas was shifted so far out of alignment with the other two that when the gamut was changed it changed the overall shape of the destination gamut. You would be able to notice a miscal like this easily from a colorcast in the whites and grays ("wow...my whites look blue"). Doesn't happen to that extreme all that often. At work, I use a Graesby Colorimeter to precisely adjust 24" color proofing monitors to match the color brightness/temperature to the lighting of the press room (luminance or b&w component) and then adjust color fidelity to match inks on our color of newsprint(chrominance). For most people at home, we are just guessing really (unless you have something like a Monitor Spyder). You are counting on your eyes to do the calibration. Problem is, we all see b&w and colors a little bit differently. Some people are more sensitive to blue, others red, etc. We also subconciously prefer colors to be a certain way. Some of us like warmer tones while some colder and that will effect what we see as a "neutral" gray when doing the calibration. So there are going to be variations across all our monitors that we all just have to live with. -=>Donald