I have my monitor at 1280x1024 and I set my wireview to 1100 pixels wide or 900 pixels high when working. If I have a nice pov I write the settings down somewhere or I give the user cam the settings I want to keep. If I need to do some close-up work I change to a nice working pov with the director cam. I center the cam to the selection when I like to move around things. Then at the final render I set up the res I like. I always make sure I have plenty of detail in the textures or on the models when I work on a scene that's going to be high-res, so it still looks good if I zoom in. I also like to model objects in an empty scene so I can get a nice detailed view. When I make big models I even split them up in several parts. I can always puzzle everything together later. For postwork I use the zooming options all the time to zoom in on the important area's or zoom out for a good overview.

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