Moving any obj (geometry) files is generally not a good idea. Nor the texture files. But as far as Pose files (Pose / MAT / MOR) I tend to condense them into similar folders rather than the vanity folders. V2 characters, V2 Clothes, Hair, M2 Clothes, Shoes, Animal Poses, etc. What can happen tho is depending on how the file is named, you may have to rename the file if others that you put into the same folder have the same name (like pose01 or whatever) OR if the file name is very general, you may lose track of the creator since you'll be ditching a vanity folder.

There are those folk who use Pboost which can create/use additional library folders, but I don't have it, so I'm not familiar w/how it works.