When trying to squeeze my file sizes down I first of all create the biggest render in poser and save as a .PSD In photoshop I do my postwork and save the psd. I then create a second copy of the psd and flatten it then save as a Jpeg. I then do a resize of the image to around about 1000 pixels wide to reduce the amount of side scrolling when posted to the galleries. When I save again I jump across to windows explorer to check the filesize of the image (don't trust the size quoted in photoshop) If too big I then go back to photoshop and then do file jump to image ready. In image ready I choose 4 up and look at the 4 options make some adjustments to 1 of them to give a better compression but still keeping the high quality and then save. I used to make the mistake of only rendering the poser file to 1024 X 768 and save as a tiff. The problem I had with tiffs is that every now and then I would have gaps left in the render (don't know why?) since I have increased the render size to the maximum size in poser 4 and save as a psd I have not had that problem.