For Vue, the punch line is, "The more is better." Vue is very sloppy when it comes to sharing CPU cycles and memories. So, the "best" would be the fastest CPU on the market and the max memory it can take. (Since you asked for "BEST".) Video card I suggest one of the top of the line ATI products, just make sure it is capable of Open GL. NVIDIA vedio cards seems like doesn't work well with Vue. I personaly like Intel and their products. And of course first and formost thing is how much you want to spend and what can be found on that price range! Hope it helps.