I used to do comics, and I hated working on the boards. But I did all my inking and coloring on the boards, and used halftone overlays for anything that required it. Damn, my memories lousy, but as I recall, my publisher them used some kind of machine that took a photo of it, and reproduced it on a thick sheet of plastic that was then used to drive the Xerox printer. I never did learn much about the process unfortunately, but if you're going to want to print your work, most printers prefer you deliver high quality Tiffs saved on CD or zip media. This is so they do color adjustments and transparency adjustments on the various channels. You might also want to look into getting a color safe palette to use in photoshop. If you have a printer in mind, he can perhaps supply you with a photoshop compatible palette that you can plug in to make sure your colors match the colors he has available for printing. There are several palettes and different printers prefer using different palettes. jje's 150 ppi should be suitable for almost any printer.

Talent is God's gift to you. Using it is your gift to God.