That's quite a system, two things I'd suggest. 1) a higher wattage of PSU, at least 400W, mebbe 450W poss as much as a 500W, with those power hungry components you're better with a beefier PSU. 2) I think one of the ATI cards would be a better bet, the nVidea cards are designed for games, where as the ATI cards are more all round cards, if you are able to afford it I'd go for the Radeon 9800 Pro 256MB one. Hope this helps.