I talked to Tech support last night, very fast response. They recommended running defrag on my system (I had very large runtime folder 15+gbs) and suggested I not load Cachemann v5.11 to see if the memory manager is causing the issue. Only then they suggest uninstalling Poser5 and reinstalling it (note it will not touch content in runtime, only files it installs) then reinstall SR4. (for those who wish to backout to SR3 you can install this instead). They indicated the SR is cumulative but it prefers clean Poser 5 install. I had to do this for SR3 when it came out so my systrem (OS is ME) was already suspect. I'll let you know if it works.