You can't calibrate your camera, but you can (under certain programs) import a color profile for your camera. I have no idea if the Coolpix 4300 has any profiles available and most of the software that use it are higher end and require you to takes your shots in RAW mode. Every digital camera and scanner adds some color cast, shift in contrast, etc. to an image. It's just the nature of the device. You need to compensate for that in your post processing. You get somewhat automatic correction of these device specific things using a device color profile. Also, every digital camera and scanner (with the exception of the Sigma SD9 and SD10 Digital SLRs) will output a somewhat soft image - nature of the Bayer pattern of the imaging array; although I think I remember the Nikon Coolpix cameras use a weird CMGY pattern instead of RGBG). Many digital cameras try to compensate for this with in camera sharpening (I don't apply any sharpening in camera to my photos, I want full control of that). Finally, almost every digital camera will need at least some level or curves tweaking to pull the black and white point to where the image looks good; stops the image from looking dull and flat. In-camera settings are made to be OK in most situations, so there is room to improve it with your post processing. Sorry if this isn't too clear. Just spent 5 hours working on a laser imager and my mind is sort of jumping around. -=>Donald