I find picking colors used in the background and scene help make a more natural light. I think that is how HDRI lights are put together, not sure. I find too many lights are a waist of time. 2 or 3 well placed lights work better, with one properly adjusted shadow cam and settings. This also gives you room to add extra lights for lamps and stuff without taking away the original effect. Yet still keeping the proper shadows that happen with multi light sources. Lets face it. No matter what you have in a scene, or how much time you spend on the render, it still needs well thought out lighting to make it work.