From what I've heard only two games extensively use Poser characters (Tribal Rage and Might and Magic 8) - however, the Zygote figures have shown up a lot in other games, rendered with other engines - let's face it, if your choices are: 1) spend days or weeks weeks modelling, jointing, etc. your own character models, 2) buy a good figure from Zygote for less than $1000USD or 3) buy a SLIGHTLY better one from Viewpoint for three to seven times that and you're limited by both a deadline and a tight budget, which would you choose?