If you leave the default RuntimeLibraries alone Poser 5 loads faster. After that copy all of the Geometries into the default Runtime (there doesn't seem to be a limit to the size on this), you can pretty much reorganize to your hearts content, without worrying about breaking anything or long load times. Poser 5 reads the RuntimeLibraries folder on startup. Hope this helps. Having a total of around 60 gigs of files for Poser, every bit helps for me. Currently all of my downloaded content sits in a seperate location from my Poser install.