I side with numanoid on this, with one slight exception. If you intend to add effects and additional sound in an external editing program (such as Adobe Premiere, Sony Vegas, or similar) before converting it to MPEG2 (for TV-type DVD viewing), then you might not want to compress the initial rendered animation at all. Instead, use "Full frames uncompressed." That way, you have the best possible quality going into your editor and won't be recompressing something that has already been compressed. The drawback, of course, is that "full frames uncompressed" will take a lot of disk space. If you don't have a lot to spare, then yes, go with numanoid's suggestion of compressing as little as possible.