What Freebass said is the usual way to go. It can lead to some heavily cluttered scenes if you intend to create a large scene. Especially if you intend to use more than two figures. Adding props and clothing when there are multiple figures in a scene can get confusing.
My approach is to create each character I'm going to use individually first. I load, texture, dress and then roughly pose each figure to something close to the final pose I'm going to need, then save it to a 'Models' folder on my drive. (I don't save these back to my figure library as they only ever get used once for the scene I'm working on.)
Once I have the basic characters prepared I start building the scene using my Key figure (the one that will be the focus of the image) and arranging props, furniture, temple or whatever around that one. Once the scene starts taking shape I then Import each additional pre-made pre-dressed figure and place them in relation to the first.
Posing them together, holding hands for instance, is the hard part and just comes down to a lot of hard work and patience with the parameter dials. Learning to actually Pose with Poser takes a while.
There are lots of couples type Pose sets available in the Marketplace if you want a quick solution.
Hope some of this helps. :o).

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