"That sounds like something is corrupting either the .dyn file or the temp file generated during the simulation. Is there anything running in the background that 'protects' you from file changes?" Hmmm. Not on this machine, which I only use for 3D animation. I've also experienced the deletion of a dyanamic solution on one item in a PZ3, but not on a second item that was in the same file, and calculated seperately. For instance, the dyanmic blouse will "lose" it's simulation when saved and reopened, but the dyanamic skirt on the same figure works just fine. I don't know if this is related to the original problem of simulations just dropping out at a certain point, but the two issues combined are KILLING me here. Doesn't happen all the time, but when it does, it makes me wanna poke my eyes out and mail them to CL. LOL

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Tools :  3dsmax 2015, Daz Studio 4.6, PoserPro 2012, Blender v2.74

System: Pentium QuadCore i7, under Win 8, GeForce GTX 780 / 2GB GPU.