I have a 4 by 5 intuos on a PC PIII-450 on usb port and was working with WIN98SE and now i use with WIN ME.Intuos have a better contruction,better resolution than the Wacom Graphire model ,and more goodies like programmable menus on the tablet.But the graphire one is very nice and less expansive;i have tried it some days before i change for Intuos because i wanted to buy mouse4d from Wacom(i finally bought this mouse and i regret now).Have fun!i can not draw now without a pen