yup, I use a mac and use stuff marked as "pc only" all the time....... it usually all works fine......sometimes you may have to edit the paths, like mentioned above, but even that is really rare, and for the most part people usually (in my experience anyway) put the "pc only" if they haven't had someone on a mac test it. The only time its different is if you have bought something at Daz, then you need to download the .sit file instead of the .exe file, because their files are put in by installers. HTH! ;)