Windows XP pro SP1 here. Like Rochr I have only ever had one virus and that was my fault (it still wasn't able to deploy though as i had patched the vulnerability it tried to exploit).

ZoneAlarm (with pretty heavy restrictions and everything has to ask permission)
McAfee VirusScan Online (updated weekly) and a bi-weekly crosscheck with Trend Micro's Housecall
AdAware SE (with biweekly crosscheck with SpySweeper)
All OS updates handled by MS Baseline Security Analyzer
Serious passwords (16-24 char) on all admin level accounts
Mozilla for browser/mail

Message edited on: 02/22/2005 20:57

Pass no temptation lightly by, for one never knows when it may pass again!