I'm with Dann-O on Metasequoia. Wings runs too slow for me in Windows, so I never got into it. C4D is pretty good as well.

"Best" is surely the interface that's least in the way of doing the job (Truespace, for example, is a pain because your mouse is worked to death pointing and clicking on fiddly little icons). But I'll leave it at that so as not to waste any more of laughingnome's valuable time :)

m.