It sounds as if you may have something in your runtime which is
conflicting with Poser. When you reinstalled, did you remove your
runtime library? If you still have content in your runtime, try
moving your runtime folder to elsewhere on your HDD and rename it
(e.g. "runtimebackup" so poser doesn't locate it. Then try
reinstalling again and see if Poser will launch. I seem to recall
having this problem a couple of years ago in Poser 5 with a freebie
folder which had used some "illegal" characters in filenames.
Unfortunately I had done a complete reinstall before someone
suggested this solution to me >.

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"you are terrifying
and strange and beautiful
something not everyone knows how to love." - Warsan Shire