I had the same thing. I have tried the RDNA solution and it seems to work. My own solution was to remove unused morphs from figures in the scene. That worked, too, but it did also induce catalepsy, and the trouble was that the corruption didn't seemed to be linked purely to the size of a file. The second time I saw this, the file was much smaller than the reduced file that had worked OK the first time. I've only ever had the problem with scenes containing multiple figures, i.e. more than one person figure, plus clothing item figures etc.. I got to the stage of saving a file with a new name after every significant change, which amounted to serious space on the drive. I suspect a dastardly plot by the manufacturers of hard drives.