Save imported objects (pz3s) as .VOB after editing the materials. You'll lose the connection with Poser, but the .VOBs are much less resource intensive - allows for more complicated scenes. Don't import a complex .pz3 all at once. Create different .pz3s (containing one figure and its clothes each) from the main .pz3 and import those separately. Reduce the amount of texture maps by replacing them with procedural materials wherever possible. Human skin: hook up the bump channel to the skin texture at strength 0.02. Replace cornea texture by a water shader without bump (and set the refraction index to 1.35).

The pen is mightier than the sword. But if you literally want to have some impact, use a typewriter

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