Interesting turn this thread has taken. By 'reloading my Runtime', I took the Runtime folder that I'd moved elsewhere when I deleted Poser and moved it back. I have not yet reloaded any updates to Poser - I didn't want to waste my time if something in my Runtime or just the size thereof was crashing it. Before I reloaded, I got a grey screen with the initial Curious Labs splashscreen - now I just get the grey screen with a taskbar on top - no splashscreen - and then it disappears. This happens whether I click Poser.exe OR a .pz3 file. BTW, I have DAZ Studio on my drive as well, but don't know enough about running it to make it work well for me - so it's not an option.