The FX5200 is quite happy in regular Windows XP, it doesn't require (and predates) 64 bit operating systems, if that's what you mean. If you have an AGP slot use that - it makes the data transfer faster than PCI (they are different slots - you can't put an AGP card in a PCI slot or vice-versa): if you mean you have a PCI-E slot that's even better, but again the card has tomatch the slot type. I'm getting decent performance from an FX5200, Athlon 1700XP, 768MB RAM, Win XP Home if that helps you assess your system.