The larger your runtime the longer it takes to open Poser. Try creating an empty runtime and have that as your active runtime when you log out of Poser. When you open Poser it shouldn't take very long to open.

"It is good to see ourselves as others see us. Try as we may, we are never
able to know ourselves fully as we are, especially the evil side of us.
This we can do only if we are not angry with our critics but will take in good
heart whatever they might have to say." - Ghandi