I'd also suggest setting up as much as your script as possible outside of Poser. This is especially true for the TkInter stuff since Poser seems to not handle these types of problems very well. I've been using PythonWin to setup and test the GUI parts of the scripts with just 'pass' stubs in the callback handlers. After all that works, I go back in and add the Poser related code. It has saved me lots of headaches.