Actually it seems to work a lot better.  I have always had problems with poser, hanging up and just not working, (I have Poser 5), but it really does seem to do better in Vista.   I just rendered a scene that I had given up rendering under win XP because it always hung up, but not only did I render the scene, I am have rendered it a second time changing the camera angle, and no hang ups.  If for no other reason this would make Vista something that I would have to have!