I have gotten side tracked over the last few weeks and have been playing with the demos versions of both. If your going to do just 2d I think you should try and then buy both. Moho is 99 dollars. Toon Boom studio is 299. Moho has bone rigging the allows you to animate charters fast. Toon Boom has a 3d space and pegs to move things about in that space. If you export charters in a png file format with alpha channel, then import into Toon Boom with backgrounds and fore ground objects. You now have a very powerful 2d animation setup for only 400 dollars.

Don’t bother with express. It has a memory leak in the program and will crash all the time. The studio has fixed the bug.

Dale