Did you apply SR3? It's available at e-Frontier.

Do you have Quicktime installed?  I heard that causes major issues.

I also remember someone having trouble with the way they had their display screen set. I think they had it set to 16 bit, but once they changed it to 32bit true colour, it worked better.

Have you updated your video drivers?

Have you gotten the Windows Updates?

Have you done a virus scan?

Do you have an earlier version of Poser as well? If so does that version work ok?

Have you checked this forum for posts about the issue? Maybe someone else posted with similar problems:

http://market.renderosity.com/mod/forumpro/showforum.php?forum_id=10139

"It is good to see ourselves as others see us. Try as we may, we are never
able to know ourselves fully as we are, especially the evil side of us.
This we can do only if we are not angry with our critics but will take in good
heart whatever they might have to say." - Ghandi