An odd little bit of personal experience: Partly as a result of desk layout and stuff, when Mice first appeared I got into the habit of using my mouse left-handed. I now use a graphics tablet, right handed. People have told me they've had problems going from mouse-style control to pen/tablet style. Well, I reckon a part of it all, is to do what you can to make the tablet different. I find I can sit back a bit, and almost relax, almost like an artist with a sketchpad. I want to get over that computer-geek-mouse-keyboard headspace. In fact, it's probably worth getting some pencils and a small sketchpad, and just doodling.