Hmm..... Have you run a registry cleaner recently? V5I is more dependant on the OS than other versions, so it is possible that some bit of dangling COM garbage is interfering; not so much as Vue killing Poser, but the Vue install affecting the OS to kill Poser. If you -do- decide to reinstall Vue, go into regedit and search the registry for anything relating to Vue or e-on and delete it before you reinstall.