Having rendered to a new window, you then use File>Save last render to save the image.

When you say you get a Browse option with Render to file, what does the dialogue look like? It should be as tandrad Windows file dialogue - big area showing the current files, entry line for you to ttype a name, drop-down list to select file type. Does the filename space not appear, or not accept typing, or fial to update the Render settings dialogue? Or do you not get a proper save dialogue?

As I said above, the Save as button on the Content palette is active only when viewing a DAZ|Studio content directory. If you are looking at a Poser content directory (which is likely if you are using Victoria 3 and clothes) then it is greyed out.

Hardware is the same as OpenGL - using the graphics card to render the image. 3Delight is software, using a Renderman compliant engine to render and supporting features not available in OpenGL.