@Daniel1705:

You didn't mention running scumware apps, just anti-virus. I've discovered however that PC Tool's 'Spyware Doctor' causes both Poser 6 and Vue 6i to crash (not Vue5i).

Have you tried V6 with nothing else running? Are you running 64 bit or 32 bit? I think 32 bit may be (not for sure) more stable.
Have you checked your display driver's OpenGl setup?

Perhaps it's an OpenGL problem? If so, try running with the folowing: (but stay in OpenGL hardware acceleration):
Options > Display Options > Enable Background Draw Thread - disable
All viewports: set to "Filled box".

If you still get crashes and want to see if it's still OpenGL related, go to ''Wireframe" in Options > Display Options'

If it is OpenGL, try for better display drivers or a newer BIOS (if one is out yet). Maybe wise to also see that you have the latest Microsoft Direct-X, though Vue is OpenGL.

HTH