I have 11 Runtime folders located out on one of my external hard drives.  I load these as I need them and unload them when I'm done.  The only content in my Poser install is what came with Poser.  This allows my Poser to load in about 30 seconds since it doesn't have to look at all the content.

Hugz from Phoenix, USA

Victoria

Remember, sometimes the dragon wins. Correction: MOST times.