A workaround would be that Prpc should only be run when needed (when "Open with Poser" is called). I'm working on fixing it that way. 
The PoserPyhton plugin alone could fix the prob, no need of a P3dO update. I'll post it in Free Stuff when done.

The reason why "'Run Python Script" is an option in P3dO is explained in P3dO's PoserPython plugin help file (security reason). 

yarp
www.senosoft.com

Yarp - author of P3DO Organizer for Poser