There are some issues.
Dynamic cloth has been reported to have some problems, especially when using multiple dynamic cloth items in one scene.
The DPI issue thefixer mentions (which is easy to work around, just multiply the height/width of your image by the DPI number, and enter the result as pixels).
Saving an image as .JPG always saves at low quality, with artefacts.
Some users have reported sluggish user interface response. 
When deleting an object/figure, Poser 7 needs some time to organize its undo buffer
The advanced hardware shaded preview doesn't work on every OpenGL enabled graphics card, and can slow things down horribly, even on fast (nVidia 7900GS) to very fast (nVidia 7800GTX) graphics cards.

None of these issues will prevent you from making the scene and rendering it, except the dynamic cloth bug.

The new features (standalone renderer, memory usage of up to 4 GB, the morph tool, collections) are very nice indeed. They offset the issues IMO.

The issues are known at e-frontier and they're working on a service pack. Expected to be released somewhere in March.

The pen is mightier than the sword. But if you literally want to have some impact, use a typewriter

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