Generally, there will be the D|S Content folder and a Runtime folder for poser items and along side that. 

My folder locations are 
DAZ>Studio>Content>Content  for D|S items and 
DAZ>Studio>Content>Runtime for Poser

Though I load both types of files to the DAZ>Studio>Content path

Some tiles I've found (mostly with freebies) will load to the content folder, but you will have to manually put them where they belong (IE, they're either stuck all in one folder that doesn't have a proper path, or they're not in a folder at all and make a big mess). So it can take some patience to organize your folders...However, as GKDantas already stated, you can have as many Content folders as you like/need to organize your stuff, just point your Winzip programs to the riht locations and make sure your D|S locations are set properly.