No. All drives partitioned as NTFS or FAT32 have a special sector for recovering the primary boot sector. It's a backup of the primary boot sector, sector 0. The backup sector tends to be the very last sector on the HD. You can use a program like DiskProbe.exe that will allow access to that backup sector. But even if you don't have that program or can't find it, knowing the exact size of the partitions you can manually rebuild that sector 0. If the sizes match precisely you should have full access to the drive again.

The best bet would be to use the built-in backup copy of the boot sector which all NTFS drives have.

Here is a Microsoft article how to do it (http://support.microsoft.com/kb/153973). Also doing a google search "Recovering NTFS Boot Sector on NTFS Partitions" should come up with other how-to's. There's another program called ZAR, but I never used it, but have heard it can also help, but I think ZAR is a bit more involved.

I hope these things help. But if they just screw it up even more, then you might be well on your way of destroying that data instead of recovering it ;-)