I have had a variety of problems with Poser and Vista and they seemed to all clear up when I turned off the OpenGL. My partner is a programmer at MS and got me the copy of Vista and now regrets it. I would encourage anyone to avoid it until version 2. I don't think the problem is Vista - it is that so much of the other things that Vista relies on are not ready for it. Change your render engine away from openGL and you should be fine.