And all my mail goes through AVG which auto-updates daily, plus I have Spybot, Ad-Aware and A Squared by EMSI.

Fro the sake of arguement through, I am going to give my Work machine a good scan with Asquared. It is protect by a spam filter by MX Logic, Mcafee (No choice there), Spybot and Ad-Aware. Plus we have a consulting firm for tech support.