Looks like nothing in the world to me so much as a lip texure superimposed over the lips on the original face. Are you copying/dragging the lip layer to a new image (where it might not be positioned correctly), or are you hiding layers and saving copies (so the lips don't budge)? What seems odd is that the shape of the glossy lips is so different from the lips of the underlying model which undercut in the middle as well as he overlap you mark. If you're sure the template isn't moving, why don't you import the obj file into UV mapper, just to be sure the template is right? Sorry - don't fee like I've been very helpful.