Hutton: two tips for getting accurate feedback.

1. Posts screenshots of the problem (press Printscreen on your computer, go into a 2D paintprogram; save then upload it here) The most helpful screenshots are of the problem themselves, render settings, and if you're in the material's room---your material settings. 

2)Be as specific as you can be. Is it dynamic clothing or conforming clothing you're working with? Yes, when you pose your character, the clothes will move out of place and poke through occurs.

If it's dynamic, here are some tutorials:

http://renderosity.com/mod/forumpro/showthread.php?thread_id=2665209
http://renderosity.com/mod/forumpro/showthread.php?thread_id=2517340&page=1
http://www.runtimedna.com/photos/File584.pdf
http://www.philc.net/CC_sampleVideo.htm

Also, start with a Zero pose. If when you load the character into the screen, their hands are by their sides...that's not a zero pose. To zero your character, press on the hip or body of the character, go to your MENU bar and press FIGURE===>USE INVERSE KINETICS====> UNCHECK leftleg and rightleg. Next go to your WINDOWS====>JOINT EDITOR====> (at the bottom) press ZERO FIGURE.