No, in the case of Poser up to version 5 you can't mix settings (poses, lights etc.) and items (figures, props etc.) though you can combine different kinds of setting and different kinds of item. Poser 6 allows you to mix all content types. I don't lnow about 7. However, for Poser (up tp version 6 at least) you have to change the extension to match the library (cr2 in librariescharacter, for instance) which D|S doesn't like. So although both Poser and D|S allow at least some mixing of content they use incompatible methods (though if you put the changed-extension files in one folder tree so you didn't load them in D|S you could do a multi-purpose Runtime).