No point reiterating the above comments that there are no Problems running Poser on 32 or 64 bit Vista of any version.

There is a potential gotcha though. If you leave Vista's User Account Control (UAC) on (WHICH YOU SHOULD!!! **) then various updates that Poser makes to files in the internal Runtime are written to the same named subfolders BURIED DEEP IN YOUR PROFILE. This not normally a problem except for in a couple of situations. If you have multiple people using Poser on the same PC, logged on as different users then the Poser will act differently for each - this is probably what you want but you need to be aware of what is going on. Secondly, if you decide to zap your PC but before you do you copy your e frontier/runtime folder somewhere for safekeeping (DVDs or a second hard disk) then you will not be saving all the files that poser changed. You may want to locate all the files that were written to your profile (they are in C:Users{yourname}AppDataLocalVirtualStoreProgram Filese frontierruntime   or   C:Users{ourname}AppDataLocalVirtualStoreProgram Files (x86)e frontierruntime  on 64bit systems, and drop those files into your real runtime in Program Files before you save the runtime to DVD or other disk. It's quite easy, just locate the runtime folder in the profile and drop it on to the runtime folder in e frontier like you do when installing a zip. UAC will ask for permission and you say yes.

** "Why should I leave UAC on?" I hear you ask. Well, the world and his dog have been beefing on at Micro$oft for YEARS about how insecure Windows is and finally M$ DO something about it. What do loads of people do? They trun the extra security off!!! sigh DON'T DO IT, YOU KNOW IT MAKES SENSE!!!