I would suggest to any new Poser or D|S user (forgive my presumption that you are a relatively new user) to keep to a small number of basic models to start with - 1 is a good number which springs to mind. Choose V4 (realism) or A3 (slight stylization) which are very popular and go with it. V3 is also very popular. 

Also don't fill your runtime with tons and tons of stuff. Keep it simple again and use what you have to make art that you really love, not sausage machine quantity.